Chemical and biological studies on Bridelia ferruginea grown in Nigeria
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منابع مشابه
Chemical Components and Effect on Streptozotocin Induced Diabetes of Bridelia Ferruginea Benth (euphorbiaceae) Root Bark Ethyl Acetate Fraction
The root of Bridelia ferruginea is traditionally used as a treatment for type 2 diabetes. The objective of this study was to evaluate the effect of Bridelia ferruginea root bark ethyl acetate fractions (EA) on streptozotocin-induced diabetes and identify some chemical compounds. Ethyl acetate fraction (25 and 50 mg/kg/day) was administrated to streptozotocin-induced (60 mg/kg) diabetic mice for...
متن کاملBridelia ferruginea Produces Antineuroinflammatory Activity through Inhibition of Nuclear Factor-kappa B and p38 MAPK Signalling
Bridelia ferruginea is commonly used in traditional African medicine (TAM) for treating various inflammatory conditions. Extracts from the plant have been shown to exhibit anti-inflammatory property in a number of in vivo models. In this study the influence of B. ferruginea (BFE) on the production of PGE(2), nitrite, and proinflammatory cytokines from LPS-stimulated BV-2 microglia was investiga...
متن کاملToxicological evaluation of the aqueous stem bark extract of Bridelia ferruginea (Euphorbiaceae) in rodents
Bridelia ferruginea is a woody shrub that grows in the Savannah or rain forests of Africa and has traditionally been used to treat diabetes, arthritis and boils. Despite all these uses, extensive toxicological evaluation has not been carried out. The aim of the present investigation was to evaluate the sub-chronic toxicological effects of the stem bark aqueous extract of Bridelia ferruginea in ...
متن کاملAntifungal Screening of Bridelia ferruginea Benth (Euphorbiaceae) Stem Bark Extract in Mouthwash Formulations
The plant Bridelia ferruginea Benth (Euphorbiaceae) has been known for its use in the management of oral thrush ethnomedicinally in various parts of Africa, a practice which has been justified by results of certain scientific studies. The aim of this study was to develop an appropriate dosage formulation, a mouthwash and evaluate the antifungal potential of this dosage formulation against a maj...
متن کاملIn vitro Toxicological Evaluation and Effect of Bridelia ferruginea Benth ( Euphorbiaceae ) on Glycemia and Insulin Secretion in Healthy Rats
The aim of this study was to compare the mechanism of action of Bridelia ferruginea root bark hydro alcoholic extract to metformin and glibenclamide on diabetes and evaluate its safety in vitro. Materials and Methods: A single dose of B. ferruginea extract (250 mg/kg), metformin (100 mg) and glibenclamide (5 mg/kg) was administered to normal blood glucose level Wistar rats. Blood glucose and in...
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ژورنال
عنوان ژورنال: Natural Product Research
سال: 2018
ISSN: 1478-6419,1478-6427
DOI: 10.1080/14786419.2018.1440225